Ultrasound-guided quadratus lumborum block with general anesthesia for perioperative circulatory stability in colorectal cancer surgery

doi:10.4240/wjgs.v17.i8.105990

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Aug 27, 2025 (publication date) through Aug 29, 2025

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Aug 27, 2025; 17(8): 105990
Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.105990

Table 6 Detection results of stress response indicators, mean ± SD

Time point	Group	Cortisol (ng/mL)	P value	NE (pg/mL)	P value	IL-6 (pg/mL)	P value
Before surgery	Experiment group (n = 58)	120.23 ± 15.45	0.585	460.11 ± 48.12	0.611	22.45 ± 3.98	0.709
Before surgery	Control group (n = 58)	118.77 ± 16.12	0.585	455.32 ± 50.45		21.99 ± 4.32	0.709
After anesthesia	Experiment group (n = 58)	155.42 ± 18.34	0.071	505.65 ± 53.12	0.103	32.22 ± 4.54	0.049^a
After anesthesia	Control group (n = 58)	142.10 ± 17.45	0.071	475.44 ± 51.10		29.65 ± 5.22	0.049^a
1 day after surgery	Experiment group (n = 58)	180.42 ± 20.34	0.026^a	530.65 ± 55.32	0.065	38.55 ± 5.41	0.008^a
1 day after surgery	Control group (n = 58)	160.22 ± 18.44	0.026^a	495.10 ± 52.11		34.23 ± 5.32	0.008^a
3 days after surgery	Experiment group (n = 58)	145.56 ± 17.88	0.054	495.43 ± 52.65	0.09	28.34 ± 4.12	0.037^a
3 days after surgery	Control group (n = 58)	135.44 ± 16.92	0.054	475.32 ± 50.87		26.12 ± 4.45	0.037^a
7 days after surgery	Experiment group (n = 58)	125.23 ± 15.24	0.401	465.23 ± 48.32	0.536	23.45 ± 3.88	0.358
7 days after surgery	Control group (n = 58)	120.12 ± 14.78	0.401	460.12 ± 47.89		22.78 ± 4.01	0.358

^aP < 0.05.

P indicating a statistically significant difference. NE: Norepinephrine; IL-6: Interleukin-6.

Citation: Li HJ, Ban X, Li J, Huang SQ. Ultrasound-guided quadratus lumborum block with general anesthesia for perioperative circulatory stability in colorectal cancer surgery. World J Gastrointest Surg 2025; 17(8): 105990
URL: https://www.wjgnet.com/1948-9366/full/v17/i8/105990.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i8.105990