Preoperative interleukin-17a as a predictor of acute pancreatitis after pancreaticoduodenectomy

doi:10.4240/wjgs.v17.i8.105112

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Aug 27, 2025 (publication date) through Aug 28, 2025

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Aug 27, 2025; 17(8): 105112
Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.105112

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Figure 1 Predictive effect of preoperative inflammatory data, interleukin-17A, and fluid load on post pancreatectomy acute pancreatitis. Preoperative interleukin-17A (IL-17a) concentrations were significantly elevated in patients who developed post pancreatectomy acute pancreatitis (PPAP) compared to those who did not, regardless of their fistula risk score (FRS) classification (P < 0.01). This consistent IL-17a elevation across all FRS risk categories suggests its potential role as a biomarker for PPAP following pancreaticoduodenectomy.

Citation: Zheng J, Ye WK, Wang J, Zhou YN, Yu TT. Preoperative interleukin-17a as a predictor of acute pancreatitis after pancreaticoduodenectomy. World J Gastrointest Surg 2025; 17(8): 105112
URL: https://www.wjgnet.com/1948-9366/full/v17/i8/105112.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i8.105112