Preoperative interleukin-17a as a predictor of acute pancreatitis after pancreaticoduodenectomy

Table 3 Associations between preoperative interleukin-17A levels, standard inflammatory indicators, and postoperative complications, n (%)

Variables	IL-17a ≥ 4.5 pg/mL (n = 65)	IL-17a < 4.5 pg/mL (n = 84)	P value
CRP > 5 mg/L	43.5	30.0	0.053
CRP [median (IQR)], mg/L	3.50(1.50-10.5)	1.75 (1.00-4.5)	< 0.001
WBC > 10 × 109/L	10.0	12.0	0.765
WBC [median (IQR)], × 109/L	6.20 (5.10-7.80)	5.30 (4.40-6.20)	0.002
NE > 7 × 109/L	5.0	6.0	0.924
NE [median (IQR)], × 109/L	4.00 (3.20-5.10)	3.20 (2.60-4.10)	0.002
PPAP	31.3	7.5	< 0.001
POPF	29.8	12.9	< 0.001
Biliary leak	4 (6.5)	3 (4.5)	0.678
PPH	10 (15.0)	12 (18.0)	0.543
Intra-abdominal infections	18 (27.0)	20 (30.0)	0.789
DGE	6 (9.0)	8 (12.0)	0.654
Chyle leak	2 (3.0)	4 (6.0)	0.567
Interventional drains	12 (18.0)	15 (22.5)	0.456
Major complications	25 (37.5)	28 (42.0)	0.784
Relaparotomy	8 (12.0)	10 (15.0)	0.679
90-day mortality	3 (4.5)	5 (7.5)	0.564
Postoperative hospital stays, days	18 (15-22)	20 (17-25)	0.453

CRP: C-reactive protein; WBC: White blood cell; NE: Neutrophils; PPAP: Post pancreatectomy acute pancreatitis; IL-17a: Interleukin-17A; POPF: Postoperative pancreatic fistula; DGE: Delayed gastric emptying.