Preoperative interleukin-17a as a predictor of acute pancreatitis after pancreaticoduodenectomy

Table 2 Inflammatory marker profiles before surgery in relation to postpancreatectomy acute pancreatitis development

Variables	No PPAP (n = 105)	PPAP (n = 45)	P value
CRP [median (IQR)], mg/L	2.11 (1.12–7.92)	2.12 (1.13–5.24)	0.214
IFN-α [median (IQR)], pg/mL	0.2 (0.2–0.2)	0.2 (0.2–0.2)	0.472
IFN-γ [median (IQR)], pg/mL	3.6 (0.1–6.9)	3.4 (0.1–6.2)	0.578
IL-2 [median (IQR)], pg/mL	0.2 (0.2–0.2)	0.2 (0.2–0.2)	0.467
IL-4 [median (IQR)], pg/mL	0.2 (0.2–0.2)	0.2 (0.2–0.2)	0.401
IL-5 [median (IQR)], pg/mL	0.2 (0.4–3.6)	0.2 (0.1–3.6)	0.469
IL-17a [median (IQR)], pg/mL	12.5 (5.8–28.7)	3.5 (1.5–8.0)	< 0.001
WBC [median (IQR)], × 109/L	5.66 (4.64–6.67)	5.96 (5.06–7.42)	0.070
Fluid load [median (IQR)], mL/day	600 (500-700)	800(700-900)	< 0.001

CRP: C-reactive protein; WBC: White blood cell; PPAP: Post pancreatectomy acute pancreatitis; IL-17a: Interleukin-17A.