Quality of life and outcomes in patients undergoing endoscopic papillectomy vs surgical treatment for duodenal papillary adenomas

Table 2 Histopathologic findings of lesions and preoperative laboratory indices, n (%)

Variable	EP (n = 155)	Surgery (n = 43)	P value
Tumor size, median (IQR) (mm)
Length	14.0 (10.0-17.0)	30.0 (18.0-40.0)	< 0.001
Width	10.0 (7.0-14.0)	15.0 (13.0-30.0)	< 0.001
Bile duct invasion	14 (9.0)	12 (27.9)	0.001
Pancreatic duct invasion	3 (1.9)	1 (2.3)	1.000
Neurological invasion	0 (0.0)	1 (2.3)	0.217
Vascular invasion	0 (0.0)	1 (2.3)	0.217
Lymphatic metastasis	0 (0.0)	0 (0.0)
Duodenal diverticulum	8 (5.2)	0 (0.0)	0.279
Preoperative dilatation of the common bile duct	25 (16.1)	18 (41.9)	< 0.001
Preoperative dilatation of the pancreatic duct	0 (0.0)	10 (23.3)	< 0.001
Pathology			< 0.001
No dysplasia	32 (20.6)	0 (0.0)
Adenoma/LGD	98 (63.2)	14 (32.6)
Adenoma/HGD	6 (3.9)	5 (11.6)
Adenoma/LGD with focal HGD	14 (9.0)	10 (23.3)
Adenoma/HGD with focal adenocarcinoma	5 (3.2)	10 (23.3)
Adenocarcinoma	0 (0.0)	4 (9.3)

EP: Endoscopic papillectomy; IQR: Interquartile range; LGD: Low-grade dysplasia; HGD: High-grade dysplasia.