Incidence, risk factors and outcomes for post-hepatectomy portal vein thrombosis: A retrospective study

Table 3 Univariate and multivariate logistic analysis of the risk factors for post-hepatectomy portal vein thrombosis

Characteristics	n	Univariate analysis		Multivariate analysis
		OR (95%CI)	P value	OR (95%CI)	P value
Disease
Benign disease	301	Reference		Reference
Other malignant disease	63	0.000 (0.000-Infinity)	0.986	0.000 (0.000-Infinity)	0.987
Hepatocellular carcinoma	338	1.280 (0.481-3.407)	0.620	1.416 (0.402-4.995)	0.588
Biliary tract cancer	362	3.116 (1.328-7.309)	0.009	1.131 (0.376-3.400)	0.827
Caudate lobectomy
No	798	Reference		Reference
Yes	266	1.900 (1.003-3.600)	0.049	0.585 (0.238-1.437)	0.242
Pancreaticoduodenectomy
No	1053	Reference		Reference
Yes	11	33.900 (9.884-116.268)	< 0.001	7.627 (1.390-41.842)	0.019
Portal vein reconstruction
No	974	Reference		Reference
Yes	90	12.364 (6.439-23.739)	< 0.001	6.119 (2.636-14.203)	< 0.001
Hepatic vein reconstruction
No	1055	Reference		Reference
Yes	9	7.250 (1.459-36.014)	0.015	2.314 (0.312-17.180)	0.412
Bile duct resection
No	674	Reference		Reference
Yes	390	3.646 (1.896-7.014)	< 0.001	1.169 (0.390-3.508)	0.781
Operation time (minute)	1064	1.003 (1.002-1.004)	< 0.001	1.000 (0.997-1.002)	0.772
Blood loss (mL)	1064	1.000 (1.000-1.001)	0.238
Blood transfusion
No	548	Reference		Reference
Yes	516	2.189 (1.139-4.206)	0.019	0.627 (0.253-1.549)	0.311
Pringle maneuver time (minute)	1060	1.011 (1.005-1.016)	< 0.001	1.007 (0.998-1.016)	0.111
Postoperative portal vein angle
≥ 100°	403	Reference		Reference
< 100°	189	3.185 (1.631-6.211)	< 0.001	2.457 (1.131-5.348)	0.023
Preoperative laboratory test
D-dimer (μg/mL)	1064	1.047 (0.951-1.153)	0.347
Postoperative laboratory test
Platelet count (9 × 104/μL)	1064	0.991 (0.986-0.996)	< 0.001	0.996 (0.990-1.002)	0.242
PTINR	1064	1.237 (1.032-1.483)	0.022	2.191 (0.826-5.814)	0.115
D-dimer (μg/mL)	1064	1.027 (0.998-1.057)	0.071
FDP (μg/mL)	1064	1.005 (0.998-1.013)	0.147

PTINR: Prothrombin time-international normalized ratio; FDP: Fibrinogen degradation product; OR: Odds ratio; CI: Confidence interval.