Incidence, risk factors and outcomes for post-hepatectomy portal vein thrombosis: A retrospective study

Table 2 Comparison of clinical characteristics between post-hepatectomy portal vein thrombosis group and none post-hepatectomy portal vein thrombosis group

Characteristics	PH-PVT	Non-PH-PVT	P value	Method
n	42	1022
Age (n)			0.534	χ2
< 60	24	534
≥ 60	18	488
Gender (n)			0.322	χ2
Male	23	637
Female	19	385
BMI, median (IQR)	23.05 (21.70, 25.22)	23.24 (21.22, 25.39)	0.944	Wilcoxon
Diseases (n)			0.003	Yates’ correction
Biliary tract cancer	25	337
Hepatocellular carcinoma	10	328
Benign disease	7	294
Other malignant disease	0	63
Liver cirrhosis (n)			0.098	χ2
Yes	10	371
No	32	651
Major hepatectomy (n)			< 0.001	χ2
Yes	38	556
No	4	466
Caudate lobectomy (n)			0.046	χ2
Yes	16	250
No	26	772
Pancreaticoduodenectomy (n)			< 0.001	Fisher test
Yes	6	5
No	36	1017
Portal vein reconstruction (n)			< 0.001	Yates’ correction
Yes	20	70
No	22	952
Hepatic vein reconstruction (n)			0.046	Fisher test
Yes	2	7
No	40	1015
Bile duct resection (n)			< 0.001	χ2
Yes	28	362
No	14	660
Operation time (minute), median (IQR)	667.5 (532.75, 750.75)	469 (325, 637)	< 0.001	Wilcoxon
Blood loss (mL), median (IQR)	400 (200, 600)	250 (100, 500)	0.005	Wilcoxon
Blood transfusion (n)			0.016	χ2
Yes	28	488
No	14	534
Postoperative portal vein angle			< 0.001	χ2
≥ 100°	16	387
< 100°	22	167
Main portal vein diameter (mm), median (IQR)	11 (10, 12)	11 (9, 12)	0.147	Wilcoxon
Pringle maneuver time (minute), median (IQR)	69.69 (58.28, 119.49)	55 (33.77, 83.90)	0.001	Wilcoxon
Preoperative laboratory test
Platelet count (9 × 104/μL), median (IQR)	175 (130, 255)	195 (146, 260)	0.318	Wilcoxon
PTINR, median (IQR)	1.02 (0.96, 1.08)	1.03 (0.97, 1.09)	0.902	Wilcoxon
FDP (μg/mL), median (IQR)	2.50 (2.50, 3.68)	2.50 (2.50, 2.62)	0.269	Wilcoxon
D-dimer (μg/mL), median (IQR)	0.56 (0.26, 2.00)	0.36 (0.15, 0.86)	0.017	Wilcoxon
Postoperative laboratory test
Platelet count (9 × 104/μL), median (IQR)	113 (83, 168)	158 (111, 212)	< 0.001	Wilcoxon
PTINR, median (IQR)	1.24 (1.17, 1.40)	1.16 (1.08, 1.25)	< 0.001	Wilcoxon
FDP (μg/mL), median (IQR)	28.74 (21.44, 49.00)	22.10 (13.15, 33.17)	0.014	Wilcoxon
D-dimer (μg/mL), median (IQR)	11.04 (7.23, 16.60)	8.13 (5.68, 12.80)	0.004	Wilcoxon

PH-PVT: Post-hepatectomy portal vein thrombosis; PTINR: Prothrombin time-international normalized ratio; FDP: Fibrinogen degradation product; BMI: Body mass index; IQR: Interquartile range.