Underwater vs conventional endoscopic mucosal resection for nonpedunculated colorectal neoplasms: A randomized controlled trial

doi:10.4240/wjgs.v17.i6.103635

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

World J Gastrointest Surg. Jun 27, 2025; 17(6): 103635
Published online Jun 27, 2025. doi: 10.4240/wjgs.v17.i6.103635

Table 4 Study outcomes (per-protocol analysis), n (%)

Outcomes	CEMR (n = 124)	UEMR (n = 122)	P value
En bloc resection			0.014¹
Yes	117 (94.4)	122 (100)
No	7 (5.6)	0 (0)
R0			0.007
Yes	112 (90.3)	120 (98.4)
No	12 (9.7)	2 (1.6)
Procedure time (IQR), second	185 (35-900)	65 (15-610)	< 0.001²
Bleeding			0.004
Yes	13 (10.5)	2 (1.6)
No	111 (89.5)	120 (98.4)
Hemoclip (IQR)	3 (1-9)	2 (1-9)	< 0.001²

¹P values were computed with Fisher’s exact test.

²P values were computed with the Mann-Whitney U test.

CEMR: Conventional endoscopic mucosal resection; IQR: Interquartile range; UEMR: Underwater endoscopic mucosal resection.

Citation: Le QD, Le NQ, Quach DT. Underwater vs conventional endoscopic mucosal resection for nonpedunculated colorectal neoplasms: A randomized controlled trial. World J Gastrointest Surg 2025; 17(6): 103635
URL: https://www.wjgnet.com/1948-9366/full/v17/i6/103635.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i6.103635