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©The Author(s) 2025.
World J Gastrointest Surg. May 27, 2025; 17(5): 105783
Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.105783
Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.105783
Table 2 Liver transplantation criteria for combined hepatocellular cholangiocarcinoma
Criteria | Tumor size | Nodules | Vascular invasion | Risk stratification |
Milan | ≤ 5 cm | ≤ 3 | Excluded | None |
UCSF | ≤ 6.5 cm | ≤ 3 (total tumor burden ≤ 8 cm) | Excluded | None |
SEER-derived RSM[55] | > 2 cm (+ 1 point) | ≥ 3 (+ 2 points) | + 1 point | Low-risk: ≤ 2 points; high-risk: > 2 points or extrahepatic metastasis |
“Very early” stage cHCC-CCA[38] | ≤ 2 cm | 1-2 | Excluded | None |
- Citation: Zhou RQ, Yang PJ, Liu TT, Han DD, Liu XL, Liu LG, Si S, Yang SW, Xu SS, Guo YW, Tan HD. Liver transplantation for combined hepatocellular cholangiocarcinoma: Current evidence, selection criteria, and therapeutic controversies. World J Gastrointest Surg 2025; 17(5): 105783
- URL: https://www.wjgnet.com/1948-9366/full/v17/i5/105783.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v17.i5.105783