Application of omental interposition to reduce pancreatic fistula and related complications in pancreaticoduodenectomy: A propensity score-matched study

Table 3 The univariate and multivariate analyses of the propensity score-matched data to evaluate the risk factors associated with clinically relevant postoperative pancreatic fistula after pancreaticoduodenectomy

	CR-POPF (24)	No CR-POPF (114)	P value	Multivariate analysis
				OR	95%CI	P value
Age (mean ± SD, yr)	63.5 ± 7.9	63.1 ± 10.1	0.829
Sex, n (%)			0.040
Male	20 (83.3%)	70 (61.4%)		2.436	0.692-8.574	0.165
Female	4 (16.7%)	44 (38.6%)		Reference
Operation method, n (%)			0.143
LPD	4 (16.7%)	36 (31.6%)
OPD	20 (83.3%)	78 (68.4%)
BMI (kg/m2)			0.000
≥ 23	18 (75.0%)	33 (28.9%)		6.094	2.021-18.374	0.001
< 23	6 (25.0%)	81 (71.1%)		Reference
Serum bilirubin (μmol/L)	96.6 (16.1-180.4)	67 (13.8-111.2)	0.185
Serum ALB (g/L)			0.843
≥ 35	21 (87.5%)	98 (86.0%)
< 35	3 (12.5%)	16 (14.0%)
ASA score, n (%)			0.122
Grade I	11 (45.8%)	66 (57.9%)
Grade II	11 (45.8%)	47 (41.2%)
Grade III	2 (8.3%)	1 (0.9%)
Pathology, n (%)			0.196
Malignancy	23 (95.8%)	96 (84.2%)
Benign	1 (4.2%)	18 (15.8%)
Omental interposition, n (%)			0.025
Yes	7 (29.2%)	62 (54.4%)		Reference
No	17 (70.8%)	52 (45.6%)		3.145	1.040-9.509	0.042
Operating time (mean ± SD, min)	387.1±82.5	377.7±71.2	0.609
HJ DFA1 (U/L)			0.010
≥ 1000	13 (54.2%)	31 (27.2%)		1.000	1.000-1.000	0.834
< 1000	11 (45.8%)	83 (72.8%)		Reference
PJ DFA1 (U/L)			0.115
≥ 1000	13 (54.2%)	42 (36.8%)
< 1000	11 (45.8%)	72 (63.2%)
Main pancreatic duct size [n (%), mm]			0.000
≥ 3	3 (12.5%)	64 (56.1%)		Reference
< 3	21 (87.5%)	50 (43.9%)		5.663	1.456-22.033	0.012

ALB: Albumin; ASA: American Society of Anesthesiologist score; BMI: Body mass index; DFA1: Drain fluid amylase obtained on the first postoperative day; HJ: Hepaticojejunostomy; LPD: Laparoscopic pancreaticoduodenectomy; OPD: Open pancreaticoduodenectomy; PJ: Pancreaticojejunostomy.