Clinical value of extended lymphadenectomy in radical surgery for pancreatic head carcinoma at different T stages

Table 6 Univariate analysis of long-term prognosis in pancreatic head carcinoma patients at T3 stage

Variables	Number (n = 45)	yr OS (%)	3-yr OS (%)	χ2	P value
Gender				0.004	0.949
Male	22	46.8	13.7
Female	23	54.1	10.8
Age (yr)				2.192	0.139
≤ 60	22	60.2	20.1
> 60	23	43.6	5.5
CA19-9 (U/mL)				1.504	0.220
≤ 37	9	59.3	29.6
> 37	36	48.9	7.5
Operation time (h)				2.647	0.104
≤ 10	18	63.2	19.0
> 10	27	42.5	6.1
Intraoperative blood loss (mL)				0.253	0.615
≤ 800	30	49.2	16.5
> 800	15	55.9	0
Tumor differentiation				0.996	0.318
Poorly	21	39.3	8.2
Moderately-highly	24	59.9	15.0
Lymph node metastasis				5.542	0.019
Yes	34	42.9	7.9
No	11	77.8	25.9
Positive lymph node count				0.569	0.451
≤ 3	33	52.9	8.2
> 3	12	46.3	23.1
Portal vein invasion				4.141	0.042
Yes	33	42.3	7.7
No	12	72.7	24.2
Resection margin				0.035	0.852
R0	41	48.1	13.9
R1	4	75.0	0
Extent of lymphadenectomy				7.843	0.005
ELD	21	65.3	21.8
SLD	24	36.1	0
Postoperative chemotherapy				0.027	0.869
Yes	23	41.5	11.9
No	22	61.2	12.4

TB: Total bilirubin; CA19-9: Carbohydrate antigen 19-9; R: Resection margin; ELD: Extended lymphadenectomy; SLD: Standard lymphadenectomy; OS: Overall survival.