Optimal postoperative surveillance strategies for stage III colorectal cancer

Table 4 Factors affecting post-recurrence survival of participants

Factors	Univariate		Multivariate
	OR (95%CI)	P value	OR (95%CI)	P value
Age (yr)	1.015 (1.007–1.024)	< 0.001	1.015 (1.006–1.024)	0.001
Sex	0.824 (0.676–1.004)	0.054	0.842 (0.688–1.032)	0.098
Image intensity	0.971 (0.799–1.179)	0.767
Differentiation
WD/MD	Ref.		Ref.
PD/SRC/MUC	2.632 (1.779–3.137)	< 0.001	2.072 (1.553–2.766)	< 0.001
(y) pT stage
0–2	Ref.
3–4	1.146 (0.833–1.576)	0.401
(y) pN stage
1c	Ref.
1	2.139 (0.300–15.256)	0.448
2	3.363 (0.471–24.009)	0.226
Lymphovascular invasion	1.456 (1.204–1.760)	< 0.001	1.152 (0.940–1.412)	0.174
Perineural invasion	1.384 (1.141–1.677)	0.001	1.284 (1.045–1.579)	0.018
Resection margin1	1.416 (0.966–2.075)	0.075	1.266 (0.856–1.871)	0.237
Curative resection	0.296 (0.229–0.381)	< 0.001	0.331 (0.255–0.428)	< 0.001

¹Resection margin indicated circumferential resection margin, and were calculated with rectal cancer patients. OR: Odds ratio; CI: Confidence interval; Ref: Reference; WD: Well differentiated; MD: Moderately differentiated; PD: Poorly differentiated; SRC: Signet ring cell type; MUC: Mucinous carcinoma.