Optimal postoperative surveillance strategies for stage III colorectal cancer

Table 2 Factors affecting overall survival of participants

Factors	Univariate		Multivariate
	OR (95%CI)	P value	OR (95%CI)	P value
Age (yr)	1.027 (1.019–1.035)	< 0.001	1.031 (1.023–1.039)	< 0.001
Sex	0.704 (0.592–0.836)	< 0.001	0.711 (0.598–0.845)	< 0.001
Surveillance intensity	1.650 (1.400–1.945)	< 0.001	1.531 (1.295–1.808)	< 0.001
Differentiation
WD/MD	Ref.		Ref.
PD/SRC/MUC	1.832 (1.424–2.356)	< 0.001	1.660 (1.285–2.143)	< 0.001
(y) pT stage
0–2	Ref.		Ref.
3–4	1.937 (1.491–2.516)	< 0.001	1.461 (1.111–1.921)	0.007
(y) pN stage
1c	Ref.		Ref.
1	5.136 (0.721–36.571)	0.102	4.754 (0.667–33.906)	0.12
2	9.322 (1.308–66.457)	0.026	7.067 (0.988–50.556)	0.051
Lymphovascular invasion	1.607 (1.365–1.891)	< 0.001	1.256 (1.057–1.491)	0.01
Perineural invasion	1.818 (1.535–2.154)	< 0.001	1.466 (1.224–1.755)	< 0.001
Resection margin1	1.972 (1.360–2.860)	< 0.001	1.603 (1.097–2.341)	0.015

¹Resection margin indicated circumferential resection margin, and were calculated with rectal cancer patients. OR: Odds ratio; CI: Confidence interval; Ref: Reference; WD: Well differentiated; MD: Moderately differentiated; PD: Poorly differentiated; SRC: Signet ring cell type; MUC: Mucinous carcinoma.