Diagnosis of anorectal tuberculosis by polymerase chain reaction, GeneXpert and histopathology in 1336 samples in 776 anal fistula patients

doi:10.4240/wjgs.v13.i4.355

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Apr 27, 2021 (publication date) through May 19, 2024

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastrointest Surg. Apr 27, 2021; 13(4): 355-365
Published online Apr 27, 2021. doi: 10.4240/wjgs.v13.i4.355

Table 3 Patient Demographics and fistula characteristics

Total patients operated = 740	Non-TB fistula (n = 627)	TB fistula (n = 113)	P value
Sex (M/F)	545/82	99/14	0.68
Age ± 2SD (yr)	38.6 ± 11.3	39.4 ± 11.2	0.17
Follow-up: Median (Range) (mo)	27 (2-75)	34 (2-74)	0.23
Multiple tracts, n (%)	408 (65.1)	86 (76.1)	0.022^a
Associated abscess, n (%)	164 (26.2)	55 (48.7)	< 0.00001^a
Horseshoe tract, n (%)	133 (21.2)	38 (33.6)	0.0052^a
Supralevator tract, n (%))	94 (15.0)	21 (18.6)	0.32^b
Recurrent fistula, n (%)	328 (52.3)	74 (65.5)	0.0103^a
Fistula grading (SJUH Classification) Grade, n (%)	I- 85 (13.6)	I-7 (6.2)	0.0038^a
	II-96 (15.3)	II-11 (9.7)
	III-71 (11.3)	III- 4 (3.5)
	IV-281 (44.8)	IV-70 (61.9)
	V-94 (15.0)	V-21 (18.6)
Fistula healing-after first surgery	499/556¹ (89.7)	78/102² (76.5)	0.0005^a
Reoperations (healed)	25 (19)	16 (12)	0.0001^a
Fistula healing-overall	518/556¹ (93.2)	90/102² (88.2)	0.101^b

¹71 patients had short follow-up or lost to follow-up.

²11 patients had short follow-up or lost to follow-up.

^aSignificant.

^bNot-significant. TB: Tuberculosis; SJUH: St James University Hospital.

Citation: Garg P, Goyal A, Yagnik VD, Dawka S, Menon GR. Diagnosis of anorectal tuberculosis by polymerase chain reaction, GeneXpert and histopathology in 1336 samples in 776 anal fistula patients. World J Gastrointest Surg 2021; 13(4): 355-365
URL: https://www.wjgnet.com/1948-9366/full/v13/i4/355.htm
DOI: https://dx.doi.org/10.4240/wjgs.v13.i4.355