Retrospective Study
Copyright ©The Author(s) 2021.
World J Gastrointest Surg. Feb 27, 2021; 13(2): 127-140
Published online Feb 27, 2021. doi: 10.4240/wjgs.v13.i2.127
Table 1 Patient characteristics from both cohorts
Parameters
Derivation cohort, n = 74
Validation cohort, n = 162
P value
Age in yr, median (IQR)61 (52-66)57 (20-63)0.063
INR, median (IQR)1 (0.95-1.07)1.05 (1-1.1)< 0.001
PT in s, median (IQR)12.5 (11.8-13)11.7 (11.2-12.5)< 0.001
TT in s, median (IQR)18.5 (16.8-19.5)18.4 (17.2-19.1)0.426
Platelet as 109/L, median (IQR)165 (125-232)156 (116-214)0.547
Albumin in g/L, median (IQR) 43 (39.4-45.7)44.3 (40.3-47.2)0.103
ALT in U/L, median (IQR)25 (18-38.8)26 (20-37)0.644
AST in U/L, median (IQR)24 (21-37)27 (22-37)0.301
TB in µmol/L, median (IQR)13.2 (9.7-19.5)12 (9-15)0.017
Cholinesterase in U/L, median (IQR)7310 (5844-8030)6968 (5981-8298)0.213
GGT in U/L, median (IQR)44 (29-99)46 (27-92)0.136
Creatinine in μmol/L, median (IQR)70 (62-79)72 (64-83)0.223
HBV–DNA in U/mL, median (IQR)8 (0-1800)0 (0-1074)0.143
HBsAg in IU/mL, median (IQR)24.9 (0-171.31)250 (0-254)0.823
HA in μg/L, median (IQR)72 (47-113)77 (44-213)0.462
Stiffness in kPa, median (IQR)9.3 (6.8-11.35)10.1 (8.0-17)0.022
Palpation scale, median (IQR)57.5 (53.3-62.8)--
Duration of surgery in min, median (IQR)258 (193-318)244 (147-328)0.382
Hospital stay in d, median (IQR)12 (7-19)7 (6-10)< 0.001
Child Pugh score, n (%)0.080
A67 (90.5)157 (96.9)
B7 (9.5)5 (3.1)
Open surgery, n (%)74 (100)67 (41.4)-
LH, n (%)-91 (56.2)-
Open convert LH, n (%)-4 (2.4)-
Major liver resection, n (%)11 (14.9)35 (21.6)0.225
PHLF, n (%)14 (18.9)19 (11.7)0.139
Grade A, n (%)12 (16.1)17 (10.5)
Grade B, n (%)1 (1.4)2 (1.2)
Grade C, n (%)1 (1.4)-
ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; FIB-4: Fibrosis-4; GGT: γ-Glutamine transpeptidase; HA: Hyaluronic acid; HBsAg: Hepatitis B surface antigen; INR: International normalized ratio; IQR: Interquartile range; LH: Laparoscopic hepatectomy; PHLF: Post-hepatectomy liver failure; PT: Prothrombin time; TB: Total bilirubin; TT: Thrombin time.