Glucagon-like peptide 1 in the pathophysiology and pharmacotherapy of clinical obesity

Figure 14 Liraglutide 3 mg shows greater, dose dependent, reductions in body weight compared to placebo and orlistat with maximal effect between 0-20 wk of treatment. Red line dotted trace shows patters of weight loss from baseline in those subjects treated with 3 mg liraglutide. Greatest rate of weight loss was observed between 0-20 wk, reducing from 20-36 with a tendency toward weight gain from 36 wk and beyond.