Glucagon-like peptide 1 in the pathophysiology and pharmacotherapy of clinical obesity

Figure 10 Effects of weight loss induced by gastric banding and Roux-en-Y gastric bypass on post-prandial glucagon-like peptide 1 secretion. Weight loss following gastric banding induces no changes in post-prandial glucagon-like peptide 1 (GLP-1) levels from pre-operative levels (A). All 7 studies assessing the effects of post-prandial GLP-1 secretion following weight loss with RYGB show significantly increased responses compared with pre-surgery responses and healthy obese controls (Bi), healthy lean controls (Bii) and following weight losses following gastric banding (Biii).