Tyrosine isomers and hormonal signaling: A possible role for the hydroxyl free radical in insulin resistance

Figure 10 The dose–response curve of the insulin-induced relaxation of consecutive arterial segments isolated from rats. The relaxation in response to insulin was the greatest in the femoral artery (n = 7) and was less pronounced in the abdominal aorta (n = 7) and even less in the thoracic aorta (n = 7). The relaxation is depicted as a function of the logarithm of the insulin dose. Data are the mean ± SEM. ^aP < 0.05; NS, P > 0.05 (Extra sum-of-squares F test). Republished with permission of Informa Healthcare from Szijártó et al[19]. NS: Non-significant; SEM: Standard error of the mean.