HLA-DQB1* alleles and genetic susceptibility to type 1 diabetes mellitus

Table 3 HLA-DQB1 genotype¹ frequency in type 1 diabetes mellitus group vs control n (%)

HLA-DQB1 genotype	Patient (n = 85)	Control (n = 113)	OR	95% CI	P value	Pc value
02/02	14 (16.5)	3 (2.7)	7.23	2.01-26.1	0.001	0.01
02/03	38 (44.7)	8 (7.1)	10.61	4.56-24.5	< 0.001	< 0.001
02/04	-	7 (6.3)	1.01	1.02-1.18	0.01	NS
02/05	6 (7.1)	4 (3.5)	2.07	0.56-7.57	0.26	NS
02/06	6 (7.1)	16 (14.2)	0.46	0.17-1.23	0.16	NS
03/03	12 (14.1)	6 (5.3)	2.93	1.05-8.16	0.033	NS
03/05	4 (4.7)	8 (7.1)	0.65	0.19-2.23	0.48	NS
03/06	2 (2.4)	22 (19.5)	0.1	0.02-0.44	< 0.00	< 0.001
05/06	1 (1.2)	11 (9.7)	0.11	0.01-0.87	0.012	NS
06/06	2 (2.4)	16 (14.2)	0.15	0.03-0.65	0.004	0.04

¹Genotypes with frequency more than 5%. HLA: Human leukocyte antigen; OR: Odds ratio; NS: Not significant; Pc value: P value corrected for 10 comparisons. Significant P value if ≤ 0.05.