HLA-DQB1* alleles and genetic susceptibility to type 1 diabetes mellitus

Table 2 HLA-DQB1 allele frequency in type-1 diabetes mellitus group vs control group n (%)

HLA-DQB1 allele	Patient (n = 85)	Control (n = 113)	OR	95% CI	P value	Pc value
02	68 (44.4)	38 (18.6)	3.5	2.19-5.65	< 0.001	< 0.001
0201	49 (32.0)	36 (17.6)	2.21	1.35-3.62	0.001	0.014
0202	19 (12.4)	2 (1.0)	14.4	3.3-62.8	< 0.001	< 0.001
03	63 (41.2)	50 (24.4)	2.17	1.38-3.41	< 0.001	< 0.001
030101	4 (2.6)	18 (8.8)	0.279	0.09-0.84	0.016	NS
030201	56 (36.6)	6 (2.9)	19.2	7.9-45.9	< 0.001	< 0.001
04	0	17 (8.3)	-	-	-
05	11 (7.2)	30 (14.6)	0.45	0.22-0.93	0.029	NS
050101	6 (3.9)	21 (10.2)	0.35	0.14-0.91	0.025	NS
050201	6 (3.3)	1 (0.5)	6.9	0.79-59.6	0.043	NS
06	11 (7.2)	70 (34.1)	0.15	0.07-0.29	< 0.001	< 0.001
060101	2 (1.3)	51 (24.9)	0.04	0.01-0.17	< 0.001	< 0.001
0603	4 (2.6)	-	2.37	2.1-2.7	0.020	NS
060401	4 (2.6)	1 (0.5)	5.48	0.6-49.5	0.090	NS

HLA: Human leukocyte antigen; OR: Odds ratio; NS: Not significant; Pc value: P value corrected for 14 comparisons. Significant P value if ≤ 0.05.