Hyperglycemia-induced overexpression of CREB3 L3 promotes the epithelial-to-mesenchymal transition in bladder urothelial cells in diabetes mellitus

doi:10.4239/wjd.v16.i8.108101

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 16, Issue 8

This Article

(50)

(58)

(0)

(1239)

(1)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Diabetes

ISSN

1948-9358

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Diabetes. Aug 15, 2025; 16(8): 108101
Published online Aug 15, 2025. doi: 10.4239/wjd.v16.i8.108101

Table 4 Top 10 differentially upregulated and downregulated mRNAs involved in the inflammation pathways of bladder urothelium that are differentially expressed between patients with diabetic cystopathy and healthy controls by RNA sequencing analyses

Ensemble Gene ID	Gene name	Log₂Fold change	P value	Regulation
ENSG00000173432	SAA1	9.14073	0.00000	Up
ENSG00000007171	NOS2	7.36349	0.00141	Up
ENSG00000102794	ACOD1	7.16781	0.00226	Up
ENSG00000163221	S100A12	7.06422	0.00001	Up
ENSG00000123838	C4BPA	6.64444	0.00071	Up
ENSG00000112115	IL17A	6.23562	0.01454	Up
ENSG00000164485	IL22RA2	6.02855	0.00162	Up
ENSG00000060566	CREB3 L3	5.75447	0.01491	Up
ENSG00000177455	CD19	5.62606	0.00004	Up
ENSG00000131203	IDO1	5.55962	0.00000	Up
ENSG00000006128	TAC1	-3.38685	0.00907	Down
ENSG00000143502	SUSD4	-2.17976	0.00717	Down
ENSG00000175344	CHRNA7	-2.17060	0.00039	Down
ENSG00000118432	CNR1	-2.08059	0.00014	Down
ENSG00000172458	IL17D	-2.01522	0.00173	Down
ENSG00000091831	ESR1	-1.97610	0.01013	Down
ENSG00000117335	CD46	-1.69696	0.00128	Down
ENSG00000132170	PPARG	-1.65880	0.01276	Down
ENSG00000107485	GATA3	-1.53300	0.00175	Down
ENSG00000168329	CX3CR1	-1.47299	0.02335	Down

Full Size Table

Citation: Wu QG, Zhang MJ, Lan YB, Ma CL, Fu WJ. Hyperglycemia-induced overexpression of CREB3 L3 promotes the epithelial-to-mesenchymal transition in bladder urothelial cells in diabetes mellitus. World J Diabetes 2025; 16(8): 108101
URL: https://www.wjgnet.com/1948-9358/full/v16/i8/108101.htm
DOI: https://dx.doi.org/10.4239/wjd.v16.i8.108101

Wu QG, Zhang MJ, Lan YB, Ma CL, Fu WJ. Hyperglycemia-induced overexpression of CREB3 L3 promotes the epithelial-to-mesenchymal transition in bladder urothelial cells in diabetes mellitus. World J Diabetes 2025; 16(8): 108101 [PMID: 40837346 DOI: 10.4239/wjd.v16.i8.108101]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.