Examining gut microbiota and metabolites to clarify mechanisms of Dimocarpus longan Lour leaf components against type 2 diabetes

Figure 1 Influence of Dimocarpus longan Lour leaf components on type 2 diabetes mellitus rats. A: Experimental protocol for the treatment of type 2 diabetes mellitus (T2DM) rats by Dimocarpus longan Lour leaf components (DLC); B: DLC treatment mitigated weight loss in T2DM rats; C: DLC therapy reduced fasting blood glucose levels in T2DM rats; D and E: The area under the curve of oral glucose tolerance test was lowered in T2DM rats following DLC treatment; F-I: Alterations in blood lipids post-DLC therapy. Results were expressed as mean ± SD (n = 6). ^aP < 0.05 vs the control (Con) group; ^bP < 0.01 vs the Con group; ^dP < 0.01 vs the model group. HDL-C: High-density lipoprotein cholesterol; Con: Control group; Mod: The model group; Met: The metformin group; HDLC: The high-dose group; MDLC: The medium-dose group; LDLC: The low-dose group; AUC: Area under the curve; OGTT: Oral glucose tolerance test. Figure 1A created with BioRender.com (Supplementary material).