Review
Copyright ©The Author(s) 2021.
World J Diabetes. Sep 15, 2021; 12(9): 1363-1385
Published online Sep 15, 2021. doi: 10.4239/wjd.v12.i9.1363
Table 7 Vitamin D supplementation versus vitamin D replacement therapy

Vitamin D supplement
Vitamin D replacement therapy
Target goalBone healthBeyond bone health
Target 25-hydroxyvitamin D level> 20 ng/mL (50 nmol/L)> 30 ng/mL (75 nmol/L)
Initial testing for 25-hydroxyvitamin D levelNoYes
Concern of over-replacementYesYes
Follow-up testing for 25-hydroxyvitamin D levelNoYes
Dose adjustmentNoYes
ApproachPublic healthIndividualized