Review
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Aug 15, 2021; 12(8): 1187-1199
Published online Aug 15, 2021. doi: 10.4239/wjd.v12.i8.1187
Progress in treatment of type 2 diabetes by bariatric surgery
Zhang-Liu Jin, Wei Liu
Zhang-Liu Jin, Wei Liu, Department of General Surgery & Department of Biliopancreatic and Metabolic Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China
Author contributions: Jin ZL and Liu W contributed to the conception and design of the study, preparation of the content, and writing of the paper.
Supported by National Natural Science Foundation of China, No. 81670481.
Conflict-of-interest statement: The authors declare having no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei Liu, FACS, MD, Professor, Department of General Surgery & Department of Biliopancreatic and Metabolic Surgery, The Second Xiangya Hospital, Central South University, No. 139 Renmin Road, Changsha 410011, Hunan Province, China. liuweixy@csu.edu.cn
Received: February 17, 2021
Peer-review started: February 17, 2021
First decision: March 16, 2021
Revised: March 29, 2021
Accepted: July 6, 2021
Article in press: July 6, 2021
Published online: August 15, 2021
Core Tip

Core Tip: Bariatric surgery is an effective treatment for type 2 diabetes (T2D), providing long-term remission. Among these types of weight loss procedures, the vertical sleeve gastrectomy and Roux-en-Y gastric bypass are extensively performed worldwide, but in the United States especially. Through establishment of reduced caloric intake and alterations in gut hormones, bile acids, and intestinal microbes, these procedures also contribute to the resolution of T2D. Understanding the mechanisms underlying the effects of bariatric surgery on T2D might provide new targets for more effective non-surgical treatments, such as medications, for T2D.