Stratification of outcomes for mucinous appendiceal adenocarcinoma with peritoneal metastasis by histological grade

Table 2 Univariate and Multivariate models using Cox regression analysis for disease-free and overall survival

Disease-free survival				Overall survival
Univariate	P value	Multivariate (HR, 95%CI)	P value	Univariate	P value	Multivariate (HR, 95%CI)	P value
Age	0.45			Age	0.35
Sex	0.051		0.59	Sex	< 0.0011		0.13
Albumin	0.27			Albumin	0.28
ECOG status	0.38			ECOG status	0.0061		0.15
Pre-op CEA	0.39			Pre-op CEA	0.07		0.51
Grade	< 0.0011	1.8 (1.2-2.8)	0.0081	Grade	< 0.0011	2.80 (1.26-6.21)	0.011
Signet ring cell	< 0.0011		0.828	Signet ring cell	< 0.0011		0.22
Lympho-vascular invasion	< 0.0011		0.15	Lympho-vascular invasion	< 0.0011		0.82
Lymph node metastasis	< 0.0011	0.42 (0.20-0.88)	0.021	Lymph node metastasis	< 0.0011		0.47
PSS	0.09	1.3 (1.1-1.6)	0.031	PSS	0.14
PCI	0.031	1.05 (1.02-1.08)	0.0021	PCI	< 0.001	1.10 (1.03-1.16)	0.0021
				CC0 resection	< 0.0011	0.32 (0.11-0.92)	0.03

¹Significant variables. ECOG: Eastern Cooperative Oncology Group; CEA: Carcinoembryonic antigen; PSS: Previous surgical score; PCI: Peritoneal carcinomatosis index.