Perioperative treatment options in resectable pancreatic cancer - how to improve long-term survival

doi:10.4251/wjgo.v8.i3.248

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Mar 15, 2016 (publication date) through May 21, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Mar 15, 2016; 8(3): 248-257
Published online Mar 15, 2016. doi: 10.4251/wjgo.v8.i3.248

Table 4 Ongoing neoadjuvant/borderline resectable trials

Trial	Registration No.	Treatment groups	Primary endpoint	Patients planned
NEONAX	NCT02047513	2 cycles Gem + nab-paclitaxel neoadjuvant	DFS	166
NEONAX	NCT02047513	4 cycles Gem + nab-paclitaxel adjuvant	DFS	166
		6 cycles Gem + nab-paclitaxel adjuvant
Perioperative mFOLFIRINOX	NCT02047474	3 cycles FOLFORINOX	DFS	46
Perioperative mFOLFIRINOX	NCT02047474	Neoadjuvant + adjuvant	DFS	46
NEOLAP	NCT02125136	2 cycles Gem + nab-paclitaxel	Conversion rate	168
		+ 2 × FOLFIRINOX		(including locally advanced PDAC)
		+ adjuvant 3 × Gem + nab-paclitaxel
		4 cycles Gem + nab-paclitaxel
		+ adjuvant 3 × Gem + nab-paclitaxel

DFS: Disease-free survival; PDAC: Pancreatic ductal adenocarcinomas.

Citation: Sinn M, Bahra M, Denecke T, Travis S, Pelzer U, Riess H. Perioperative treatment options in resectable pancreatic cancer - how to improve long-term survival. World J Gastrointest Oncol 2016; 8(3): 248-257
URL: https://www.wjgnet.com/1948-5204/full/v8/i3/248.htm
DOI: https://dx.doi.org/10.4251/wjgo.v8.i3.248