Evaluation of antibody-dependent cell-mediated cytotoxicity activity and cetuximab response in KRAS wild-type metastatic colorectal cancer patients

Table 2 FCGR2A (rs1801274; A > G), FCGR3A (rs366991; T > G) and single nucleotide polymorphism rs61764370 of KRAS 3’ untranslated region genotypes with the correspondent aminoacid change in the 41 metastatic colorectal cancer patients included in this study

Gene	SNP	Genotype	Aminoacid change	Number of subjects (%)
FCGR2A	rs1801274	A/A	H131H	14 (34.1%)
		A/G	H131R	20 (48.8%)
		G/G	R131R	7 (17.1%)
FCGR3A	rs396991	T/T	F158F	14 (34.1%)
		T/G	F158V	21 (51.2%)
		G/G	V158V	6 (14.7%)
KRAS 3’ UTR	rs61764370	T/T	---	32 (78%)
		T/G	---	9 (22%)
		G/G	---	0 (0%)

SNP: Single nucleotide polymorphism; UTR: Untranslated region.