Editorial
Copyright ©The Author(s) 2015.
World J Gastrointest Oncol. May 15, 2015; 7(5): 30-46
Published online May 15, 2015. doi: 10.4251/wjgo.v7.i5.30
Table 4 CpG island hyper- (and hypo-) methylation of DNA repair genes in cancers
CancerGeneFrequency of promoter hyper-(or hypo-) methylation in cancer
ColorectalLIG482%[78]
MGMT40%-90%[17-21]
ERCC138%[79]
WRN29%-38%[63,80]
MLH19%-10%[22,81]
FEN1Frequent (hypo-)[82]
MBD4Frequent (hyper-)[61]
EsophagealMGMT23%-79%[65,83,84]
MLH143%[82], 64%[85]
MSH229%[83], 75%[84]
StomachMGMT88%[60]
MLH173%[64]
WRN24%-25%[80,86]
FEN1Frequent (hypo-)[82]
Gastric lymphomaATM11%[87]