Novel diet-related mouse model of colon cancer parallels human colon cancer

doi:10.4251/wjgo.v6.i7.225

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jul 15, 2014; 6(7): 225-243
Published online Jul 15, 2014. doi: 10.4251/wjgo.v6.i7.225

Table 3 Comparison of diet alone to diet + deoxycholic acid on colonic tumor and cancer development n (%)

Diet	Diet (mo)	Mice	Mice with tumors(adenomas + cancers)	Mice with cancer	Tumors(tumor burden¹)	Cancers(cancer burden²)
Diet alone	10	22	0	0	0 (0)	0 (0)
Diet + DOC	10	22	20 (91%)	10 (45%)	57 (2.6)	18 (0.82)

¹Tumor burden is the ratio of the number of tumors observed to the number of mice;

²Cancer burden is the ratio of the number of cancers observed to the number of mice. DOC: Deoxycholic acid.

Citation: Prasad AR, Prasad S, Nguyen H, Facista A, Lewis C, Zaitlin B, Bernstein H, Bernstein C. Novel diet-related mouse model of colon cancer parallels human colon cancer. World J Gastrointest Oncol 2014; 6(7): 225-243
URL: https://www.wjgnet.com/1948-5204/full/v6/i7/225.htm
DOI: https://dx.doi.org/10.4251/wjgo.v6.i7.225