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World J Gastrointest Oncol. Dec 15, 2014; 6(12): 444-449
Published online Dec 15, 2014. doi: 10.4251/wjgo.v6.i12.444
Published online Dec 15, 2014. doi: 10.4251/wjgo.v6.i12.444
Table 2 Association between GNAS1 T393C single nucleotide polymorphism and clinical parameters
| Subgroup | All (n = 94) | TT (n = 38; 40%) | TC (n = 29; 31%) | CC (n = 27; 29%) | P | |
| Gender | Male | 71 | 31 (43.6) | 22 (30.9) | 18 (25.5) | 0.42 |
| Female | 23 | 7 (30.4) | 7 (30.4) | 9 (39.2) | ||
| Age | ≥ 60 yr | 51 | 22 (43.1) | 13 (25.5) | 16 (31.4) | 0.48 |
| < 60 yr | 43 | 16 (37.2) | 16 (37.2) | 11 (25.6) | ||
| Performance status | ≥ 2 | 25 | 13 (52.0) | 5 (20.0) | 7 (28.0) | 0.30 |
| < 2 | 69 | 25 (36.2) | 24 (34.8) | 20 (29.0) | ||
| Smoking | Yes | 23 | 12 (52.2) | 6 (26.1) | 5 (21.7) | 0.44 |
| No | 71 | 26 (36.6) | 23 (32.4) | 22 (31.0) | ||
| Pathology | Adenocarcinoma | 48 | 19 (39.6) | 17 (35.4) | 12 (25.0) | 0.59 |
| Squamous cell carcinoma | 46 | 19 (41.3) | 12 (26.1) | 15 (32.6) |
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Citation: Gong HY, Hu WG, Wang XL, Zhu F, Song QB. TT genotype of
GNAS1 T393C polymorphism predicts better outcome of advanced non-small cell lung cancer patients. World J Gastrointest Oncol 2014; 6(12): 444-449 - URL: https://www.wjgnet.com/1948-5204/full/v6/i12/444.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v6.i12.444