TT genotype of GNAS1 T393C polymorphism predicts better outcome of advanced non-small cell lung cancer patients

Table 1 Clinicopathological characteristics of 94 patients with non-small cell lung cancer

	Subgroup	n	MST	1-yr OS (%)	2-yr OS (%)	P
Gender	Male	71	14	59	36	0.058
	Female	23	13	53	28
Age	≥ 60 yr	51	13	61	26	0.135
	< 60 yr	43	16	52	36
PS	≥ 2	25	13	51	25	0.658
	< 2	69	17	64	32
Smoking	Yes	23	13	55	29	0.473
	No	71	14	58	32
Pathology	Adenocarcinoma	48	13	54	36	0.559
	Squamous cell carcinoma	46	14	63	29
Treatment	Supportive treatment only	12	10	49	25	0.116
	Chemotherapy	14	13	56	32
	Radiotherapy	11	13	60	30
	Chemoradiotherapy	57	16	64	35
GNAS1 T393C	TT	38	25	76	48	0.01
	TC	29	12	54	18
	CC	27	8	23	15
	TC + CC	56	11.5	25	16	0.01

OS: Overall survival; PS: Performance status.