Gastrointestinal B-cell lymphomas: From understanding B-cell physiology to classification and molecular pathology

Figure 2 Histology of gastrointestinal mucosa-associated lymphoid tissue, follicular and mantle-cell lymphomas. A: Hematoxylin eosin (HE) staining of a gastric mucosa-associated lymphoid tissue lymphoma demonstrates presence of reactive follicles surrouned by a neoplastic lymphoid infiltrate (magnification 50 ×); B: Destruction of a gastric gland by the neoplastic B-cellss: lymphoepithelial lesion (magnification 400 ×); C: HE staining of a duodenal follicular lymphoma highlights the presence of aberrant follicular growth pattern (magnification 100 ×); D: Aberrant B-cell-lymphoma-2 expression by a duodenal follicular lymphoma (magnification 100 ×); E: HE staining of a mantle-cell lymphoma in the colon (magnification 200 ×); F: Aberrant cyclin D1 expression by an intestinal mantle-cell lymphoma (magnification 100 ×).