Evidence based radiation therapy for locally advanced resectable and unresectable gastric cancer

Table 2 Phase II trials for preoperative chemo-radiotherapy in resectable gastric cancer

Author,year published	Nr Pt	Treatment schedule	PathCR rate	Quality of surgery
Ajani et al[16], 2006	49	Patients received two cycles of induction 5-FU, LV and CIS followed by concurrent CRT (infusional 5-FU and weekly paclitaxel). Resection was attempted 5 to 6 wk after CRT	27%	The R0 resection rate was 77%
Ajani et al[17], 2004	33	Patients received two cycles of induction 5-FU, LV and CIS followed by concurrent CRT (infusional 5-FU).	30%	The R0 resection rate was 70%
Ajani et al[18], 2005	41	Patients received two cycles of induction 5-FU, LV and CIS followed by concurrent CRT (infusional 5-FU and weekly paclitaxel).	25%	The R0 resection rate was 78%

Nr: Number; Pt: Patients; 5-FU: 5-fluorouracil; LV: Leucovorin; CIS: Cisplatin; CRT: Chemo-radiotherapy; PathCR: Pathologic complete response; R0: Microscopically negative surgical margins.