©2010 Baishideng.
World J Gastrointest Oncol. Feb 15, 2010; 2(2): 59-64
Published online Feb 15, 2010. doi: 10.4251/wjgo.v2.i2.59
Published online Feb 15, 2010. doi: 10.4251/wjgo.v2.i2.59
Table 1 Environmental and other risk factors for conventional gastric cancer
| Increased risk of gastric cancer | Decreased risk of gastric cancer |
| CHD1, TP53, BRCA2 germline mutation | Fruit and vegetables |
| Hereditary non-polyposis colorectal cancer | Ascorbic acid |
| Helicobacter pyloriinfection | Carotenoids |
| Ebstein barrvirus infection | Folates |
| Cigarette smoking | Tocopherols |
| Smoked or cured meat and fish | Cereal fibres |
| Pickled vegetables | Numerous polymorphisms (as mentioned under increased risk) |
| Chilli peppers | |
| Alcohol | |
| Exposure to nitrosamines + inorganic dust | |
| Obesity | |
| Pharmacological gastric acid suppression | |
| IL-1β-31 polymorphism | |
| 1195 COX-2 polymorphism | |
| Other polymorphisms: MTHFR, PSCA, XPA, XPC, ERCC2, GSTT1, SULT1A1, NAT2, EPHX1, Toll-like receptor 4 |
- Citation: Milne AN, Offerhaus GJA. Early-onset gastric cancer: Learning lessons from the young. World J Gastrointest Oncol 2010; 2(2): 59-64
- URL: https://www.wjgnet.com/1948-5204/full/v2/i2/59.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v2.i2.59