Early and long-term postoperative management following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

Table 1 Morbidity and mortality rates after cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy

Authors, yr	Patients (n)	PSM	Death (%)	Overall morbid (%)	Major morbid	Most common complications
						1st	2nd	3rd
Jacquet et al[21], 1996	60		5	-	35
Stephens et al[10], 1999	200	Mixed	1.5	-	27	Peripancreatic	Bowel perf/anast leak	Bleeding
Glehen et al[11], 2003	216	Mixed	3.2	30.5	23.6	Bowel perf/anast leak	Haematol	Prolonged ileus
Kusamura et al[14], 2006	209	Mixed	0.9	-	12	Bowel perf/anast leak	Bleeding	Sepsis
Smeenk et al[12], 2006	103	PMP	11	54	54	Infection	Bowel perf/anast leak	Cardiopulm
Gusani et al[15], 2008	124	Mixed	1.6	56.5	29.8	Reoperation	Bowel perf/anast leak	Sepsis
Sugarbaker et al[23], 2006	356	PMP	2.0	74.2	40.2	Haematol	Gastroint	Cardiovasc
Yan et al[24], 2007	70	PM	3.0	41	14	Bleeding	Resp failure	Bowel perf/anast leak
Elias et al[13], 2007	106	Mixed	4	-	66	Bowel perf/anast leak	Lung infection	Haematol
Levine et al[26], 2007	501	Mixed	4.3	43.1	-	-	-	-
Verwaal et al[22], 2004	102	CRC	7.8	65	35	Bowel perf/anast leak	Infection	Haematol
Feldman et al[27], 2003	49	PM	0	38	-	Hepatic	Renal	Haematol
Stewart et al[28], 2006	110	PMP	6	38	-	Wound infection	Haematol	Resp failure

PSM: Peritoneal surface malignancy; PMP: Pseudomyxoma peritonei; PM: Peritoneal mesothelioma; CRC: Colorectal cancer carcinomatosis; perf: Perforation; anast: Anastomoses.