Gastric amphicrine carcinoma with leptomeningeal metastases: A case report

Figure 6 Immunohistochemistry of the gastric antrum lesion. A: Chromogranin A (CgA) expression was diffusely positive (EnVision, 200 ×); B: Synaptophysin (Syn) showed diffuse positive expression (EnVision, 200 ×); C: Insulinoma-associated protein 1 (INSM1) demonstrated diffuse positivity (EnVision, 200 ×); D and E: Mucin 1 (MUC1) and MUC2 expression were both positive (EnVision, 200 ×); F: Diastase-Periodic Acid-Schiff (D-PAS) staining revealed intracellular mucin within the cytoplasm of tumor cells (Special stain, 400 ×); G: Cytokeratin 7 (CK7) expression was diffusely positive (EnVision, 200 ×); H: Ki-67 proliferation index (EnVision, 200 ×); I: Dual staining showing combined positivity of D-PAS special staining and INSM1 immunohistochemistry (400 ×).