Gastric amphicrine carcinoma with leptomeningeal metastases: A case report

Table 2 Clinical characteristics and follow-up outcomes of patients with gastric amphicrine carcinoma

Ref.	Case	Sex	Age (year)	Lesion location	Size (cm)	TNM staging	Stage	Treatment	Outcomes (month)
Li et al[14], 2026	1	Male	52	Gastric body	4.5	T4aN2M0	IIIA	Surgery + chemotherapy	AWD, 15
	2	Male	69	Gastric antrum	4.3	T3N3aM0	IIIB	Surgery + chemotherapy	DOD, 6
	3	Male	53	Gastric antrum	4.0	T4aN3aM0	IIIB	Surgery + chemotherapy	NED, 18
	4	Male	72	Gastric cardia	4.0	T3N1M0	IIB	Surgery + chemotherapy	NED, 17
Chen et al[15], 2025	5	Male	64	Gastric cardia	4.0	T3N1M0	IIB	Surgery + chemotherapy	NED, 8
	6	Male	70	Gastric cardia	3.0	T3N2M0	IIIA	Surgery + chemotherapy	NED, 49
	7	Male	62	Gastric antrum	3.0	T3N3M0	IIIB	Surgery + chemotherapy	NED, 27
Qian and Feng[16], 2022	8	Male	69	Gastric body/antrum	8.5	TxN3bM0	IIIC	Surgery + chemotherapy	NED, 6
Sciarra et al[17], 2023	9	Male	63	Gastric cardia	1.2	T1b(sm)NxM0	IA	Surgery	NED, 18
Huang et al[18], 2019	10	Male	61	Gastric body	5.5	T4N1M0	IIIA	Surgery + chemotherapy	NED, 63
	11	Male	58	Gastric antrum	NA	T2N0M0	IB	Surgery	NED, 10
	12	Male	63	Gastric antrum	3.0	T1N0M0	IA	Surgery	NED, 10
	13	Male	56	Gastric body	2.5	T4N2M0	IIIA	Surgery	DOD, 42
	14	Male	68	Gastric antrum	4.5	T4N3bM0	IIIC	Surgery + chemotherapy	NED, 12
	15	Male	60	Gastric cardia	2.0	T4N1M0	IIIA	Surgery	DOD, 11
	16	Male	67	Gastric cardia	3.5	T3N0M0	IIA	Surgery + chemotherapy	NED, 6
Gao et al[19], 2025	17	Male	59	Gastric body	1.5	T1b (sm)N0M0	IA	ESD only	NED, 6
Current case	18	Male	66	Gastric antrum	3.0	T4N1M1	IV	Immunotherapy + chemotherapy	DOD, 10

Stage is according to the AJCC 8^th edition gastric cancer staging system. AWD: Alive with disease; DOD: Dead of disease; ESD: Endoscopic submucosal dissection; NED: No evidence of disease; TNM: Tumor-node-metastasis.