Comparative study of 18F-FAPI-04 and 18F-FDG PET/CT in the initial staging and postoperative metastasis detection of gastric cancer

doi:10.4251/wjgo.120559

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Sep 15, 2026; 18(9): 120559
Published online Sep 15, 2026. doi: 10.4251/wjgo.120559

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Figure 4 A 64-year-old male with a history of gastric cancer surgery underwent positron emission tomography/computed tomography to monitor for recurrence and metastases. A: ¹⁸F-fibroblast activation protein inhibitor-04 positron emission tomography/computed tomography images displayed intensely diffuse uptake (maximum standardized uptake value = 11.8) in the peritoneal metastases (solid line arrow); B: ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography images displayed no uptake in peritoneal metastatic lesions (dotted line arrow). Additionally, fibroblast activation protein inhibitor demonstrated increased uptake in more lymph node and muscular lesions compared to fluorodeoxyglucose.

Citation: Xue XQ, Li QB, Fu HT, Hou L, Wang R, Shi X, Yu CJ. Comparative study of ¹⁸F-FAPI-04 and ¹⁸F-FDG PET/CT in the initial staging and postoperative metastasis detection of gastric cancer. World J Gastrointest Oncol 2026; 18(9): 120559
URL: https://www.wjgnet.com/1948-5204/full/v18/i9/120559.htm
DOI: https://dx.doi.org/10.4251/wjgo.120559

Xue XQ, Li QB, Fu HT, Hou L, Wang R, Shi X, Yu CJ. Comparative study of ¹⁸F-FAPI-04 and ¹⁸F-FDG PET/CT in the initial staging and postoperative metastasis detection of gastric cancer. World J Gastrointest Oncol 2026; 18(9): 120559 [DOI: 10.4251/wjgo.120559]

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