Comparative study of 18F-FAPI-04 and 18F-FDG PET/CT in the initial staging and postoperative metastasis detection of gastric cancer

doi:10.4251/wjgo.120559

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World Journal of Gastrointestinal Oncology

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1948-5204

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World J Gastrointest Oncol. Sep 15, 2026; 18(9): 120559
Published online Sep 15, 2026. doi: 10.4251/wjgo.120559

Table 3 Comparison of ¹⁸F-fibroblast activation protein inhibitor-04 and ¹⁸F-fluorodeoxyglucos in diffuse peritoneal metastatic lesions

Characteristics	FAPI		FDG		P value
Characteristics	Median range		Median range		P value
PCI	14	6-25	2.5	2-3	0.012
SUVmax	8.0	5.7-13.0	4.7	3.5-5.8	0.001
Characteristics	Primary tumors	LNM	BM	PM	LM
¹⁸F-FAPI-04	19	32	65	30	3
¹⁸F-FDG	17	25	36	6	2

PCI: Peritoneal cancer index; LR: Local recurrences; LNM: Lymph node metastases; BM: Bone metastases; LM: Liver metastases; PM: Peritoneal metastase; FAPI: Fibroblast activation protein inhibitor; FDG: Fluorodeoxyglucos; SUVmax: Maximum standardized uptake value; ¹⁸F-FAPI-04: ¹⁸F-fibroblast activation protein inhibitor-04; ¹⁸F-FDG: ¹⁸F-fluorodeoxyglucos.

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Citation: Xue XQ, Li QB, Fu HT, Hou L, Wang R, Shi X, Yu CJ. Comparative study of ¹⁸F-FAPI-04 and ¹⁸F-FDG PET/CT in the initial staging and postoperative metastasis detection of gastric cancer. World J Gastrointest Oncol 2026; 18(9): 120559
URL: https://www.wjgnet.com/1948-5204/full/v18/i9/120559.htm
DOI: https://dx.doi.org/10.4251/wjgo.120559

Xue XQ, Li QB, Fu HT, Hou L, Wang R, Shi X, Yu CJ. Comparative study of ¹⁸F-FAPI-04 and ¹⁸F-FDG PET/CT in the initial staging and postoperative metastasis detection of gastric cancer. World J Gastrointest Oncol 2026; 18(9): 120559 [DOI: 10.4251/wjgo.120559]

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