Association between lymphopenia and the survival of patients with colorectal cancer: A meta-analysis

doi:10.4251/wjgo.119140

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

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World J Gastrointest Oncol. Sep 15, 2026; 18(9): 119140
Published online Sep 15, 2026. doi: 10.4251/wjgo.119140

Table 3 Results of univariate meta-regression analysis of the influence of absolute lymphocyte count cutoffs on the outcomes

Outcomes	Influence of the ALC cutoffs
Outcomes	Coefficient	95%CI	P value	Adjusted R²
HR for the association between lymphopenia and PFS	0.00055	-0.00025 to 0.00136	0.17	37.9%
HR for the association between lymphopenia and OS	0.00024	-0.00052 to 0.00099	0.49	7.5%

ALC: Absolute lymphocyte count; PFS: Progression-free survival; OS: Overall survival; HR: Hazard ratio; CI: Confidence interval.

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Citation: Chen K, Li H, Chen HH. Association between lymphopenia and the survival of patients with colorectal cancer: A meta-analysis. World J Gastrointest Oncol 2026; 18(9): 119140
URL: https://www.wjgnet.com/1948-5204/full/v18/i9/119140.htm
DOI: https://dx.doi.org/10.4251/wjgo.119140

Chen K, Li H, Chen HH. Association between lymphopenia and the survival of patients with colorectal cancer: A meta-analysis. World J Gastrointest Oncol 2026; 18(9): 119140 [DOI: 10.4251/wjgo.119140]

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