Pathological characteristics of hepatocellular carcinoma: A dual-center correlation analysis and validation

doi:10.4251/wjgo.119082

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Sep 15, 2026; 18(9): 119082
Published online Sep 15, 2026. doi: 10.4251/wjgo.119082

Table 1 Baseline clinicopathological characteristics by center, n (%)

Characteristics	Center A (n = 157)	Center B (n = 66)	Test statistic	P value
Age (year), mean ± SD	56.0 ± 12.1	53.9 ± 10.0	t = 1.233	0.219
Sex (male/female)	136/21	52/14	χ² = 2.156	0.142
Edmondson grading (low/high)	66/91	31/35	χ² = 0.460	0.498
MVI positive	111 (70.7)	41 (62.1)	χ² = 1.576	0.209
SN present	69 (44.0)	31 (46.9)	χ² = 1.171	0.679
Ki-67 high expression	83 (52.9)	31 (46.9)	Z = -1.639	0.104

The Mann-Whitney U test was used to compare Ki-67 expression (non-normally distributed) between centers. MVI: Microvascular invasion; SN: Satellite nodule.

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Citation: Huang HB, Zhang YD, Yang J, Huang YY, Huang LF, Wang SY, Lu W, Huang ZH, Ding K. Pathological characteristics of hepatocellular carcinoma: A dual-center correlation analysis and validation. World J Gastrointest Oncol 2026; 18(9): 119082
URL: https://www.wjgnet.com/1948-5204/full/v18/i9/119082.htm
DOI: https://dx.doi.org/10.4251/wjgo.119082

Huang HB, Zhang YD, Yang J, Huang YY, Huang LF, Wang SY, Lu W, Huang ZH, Ding K. Pathological characteristics of hepatocellular carcinoma: A dual-center correlation analysis and validation. World J Gastrointest Oncol 2026; 18(9): 119082 [DOI: 10.4251/wjgo.119082]

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