Relationship of TRAP1, HMGB1, and p62 expression with clinicopathologic features in colon cancer tissues

doi:10.4251/wjgo.123088

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World Journal of Gastrointestinal Oncology

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1948-5204

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World J Gastrointest Oncol. Aug 15, 2026; 18(8): 123088
Published online Aug 15, 2026. doi: 10.4251/wjgo.123088

Table 7 Multivariable logistic regression analysis of factors associated with lymph node metastasis in colon cancer

Variable	B	SE	Wald χ²	OR	95%CI	P value
Maximum tumor diameter ≥ 5 cm	0.531	0.367	2.093	1.70	0.80-3.60	0.148
Poor differentiation	0.642	0.377	2.892	1.90	0.90-4.10	0.089
Depth of invasion T3-4	0.470	0.447	1.106	1.60	0.60-4.00	0.293
Lymphovascular invasion positive	0.916	0.417	4.828	2.50	1.10-5.70	0.028
High TRAP1 expression	1.386	0.421	10.828	4.00	1.80-8.90	0.001
High HMGB1 expression	0.788	0.399	3.910	2.20	1.00-4.90	0.048
High p62 expression	0.405	0.350	1.346	1.50	0.70-3.40	0.246

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Citation: Guo HL, Qi YP, Zhang Q, Hao JJ, Yang Y, Zhang MY, He ZT. Relationship of TRAP1, HMGB1, and p62 expression with clinicopathologic features in colon cancer tissues. World J Gastrointest Oncol 2026; 18(8): 123088
URL: https://www.wjgnet.com/1948-5204/full/v18/i8/123088.htm
DOI: https://dx.doi.org/10.4251/wjgo.123088

Guo HL, Qi YP, Zhang Q, Hao JJ, Yang Y, Zhang MY, He ZT. Relationship of TRAP1, HMGB1, and p62 expression with clinicopathologic features in colon cancer tissues. World J Gastrointest Oncol 2026; 18(8): 123088 [DOI: 10.4251/wjgo.123088]

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