Clinical value of carbon nanoparticles in identifying metastatic lymph nodes in colorectal cancer: A single-center observational study

doi:10.4251/wjgo.122077

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Aug 15, 2026; 18(8): 122077
Published online Aug 15, 2026. doi: 10.4251/wjgo.122077

Table 2 The distribution of stained and metastatic lymph nodes, n (%)

Variables	Staining (n = 146)	Non-staining (n = 146)	P value
Number of LNs	2789	423	< 0.001^a
D1	1581 (56.7)	337 (79.7)
D2	832 (29.8)	60 (14.2)
D3	376 (13.5)	26 (6.1)
Metastatic status of LNs			< 0.001^a
Non-metastatic LNs	2712 (97.2)	364 (86.1)
Metastatic LNs	77 (2.8)	59 (13.9)
Number of LNs			< 0.001^a
LVI negative	2376 (85.2)	332 (78.5)
LVI positive	413 (14.8)	91 (21.5)
Non-regional LNs (n = 9)	25	7	0.042^a
Non-metastatic LNs	25 (100)	2 (28.6)
Metastatic LNs	0 (0)	5 (71.4)
Tumor deposits (n = 16)	2 (5.3)	36 (94.7)

^aP < 0.05.

LNs: Lymph nodes; D1: Pericolic/perirectal lymph node; D2: Intermediate lymph node; D3: Main lymph node; LVI: Lymphovascular invasion.

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Citation: Bai BJ, Xu DY, Chen L, Ding LY, Song ZF. Clinical value of carbon nanoparticles in identifying metastatic lymph nodes in colorectal cancer: A single-center observational study. World J Gastrointest Oncol 2026; 18(8): 122077
URL: https://www.wjgnet.com/1948-5204/full/v18/i8/122077.htm
DOI: https://dx.doi.org/10.4251/wjgo.122077

Bai BJ, Xu DY, Chen L, Ding LY, Song ZF. Clinical value of carbon nanoparticles in identifying metastatic lymph nodes in colorectal cancer: A single-center observational study. World J Gastrointest Oncol 2026; 18(8): 122077 [DOI: 10.4251/wjgo.122077]

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