Cardioprotective effects of remimazolam in elderly hypertensive patients undergoing gastrointestinal tumor surgery: A randomized controlled trial

doi:10.4251/wjgo.v18.i8.121785

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Aug 15, 2026; 18(8): 121785
Published online Aug 15, 2026. doi: 10.4251/wjgo.v18.i8.121785

Table 3 Comparison of arterial blood gas parameters between the two groups, mean ± SD

Item	Time	P group (n = 40)	R group (n = 40)	t value	P value
SBP (mmHg)	T0	157.00 ± 19.34	153.58 ± 17.32	0.834	0.407
	T6	145.30 ± 18.10^a	144.08 ± 17.91^a	0.304	0.762
DBP (mmHg)	T0	79.88 ± 13.60	80.10 ± 10.80	-0.082	0.935
	T6	76.48 ± 10.29	73.58 ± 9.41^a	1.316	0.192
HR (bpm)	T0	74.28 ± 11.33	72.43 ± 12.78	0.685	0.495
	T6	72.85 ± 13.01	72.05 ± 11.19	0.295	0.769
Glu (mmol/L)	T0	6.16 ± 1.36	6.28 ± 1.95	-0.321	0.749
	T4	6.91 ± 1.34^a	7.32 ± 1.77^a	-1.170	0.245
Lac (mmol/L)	T0	1.08 ± 0.53	0.84 ± 0.28	2.507	0.014
	T4	0.80 ± 0.36^a	0.68 ± 0.29^a	1.714	0.091
PaCO₂ (mmHg)	T0	40.11 ± 6.27	42.29 ± 5.88	-1.608	0.112
	T4	48.34 ± 7.05^a	46.22 ± 5.56^a	1.488	0.141

^aP < 0.05 vs T0.

SBP: Systolic blood pressure; DBP: Diastolic blood pressure; HR: Heart rate; Glu: Glucose; Lac: Lactate; PaCO₂: Partial pressure of carbon dioxide; P group: Control group (propofol-based intravenous general anesthesia); R group: Experimental group (remimazolam-based intravenous general anesthesia).

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Citation: Ma TT, Tong J, Liu MY. Cardioprotective effects of remimazolam in elderly hypertensive patients undergoing gastrointestinal tumor surgery: A randomized controlled trial. World J Gastrointest Oncol 2026; 18(8): 121785
URL: https://www.wjgnet.com/1948-5204/full/v18/i8/121785.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i8.121785

Ma TT, Tong J, Liu MY. Cardioprotective effects of remimazolam in elderly hypertensive patients undergoing gastrointestinal tumor surgery: A randomized controlled trial. World J Gastrointest Oncol 2026; 18(8): 121785 [DOI: 10.4251/wjgo.v18.i8.121785]

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