Cardioprotective effects of remimazolam in elderly hypertensive patients undergoing gastrointestinal tumor surgery: A randomized controlled trial

doi:10.4251/wjgo.v18.i8.121785

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Aug 15, 2026; 18(8): 121785
Published online Aug 15, 2026. doi: 10.4251/wjgo.v18.i8.121785

Table 10 Comparison of arterial blood gas parameters between non-myocardial injury after non-cardiac surgery and myocardial injury after non-cardiac surgery patients, mean ± SD

Item	Time	Non-MINS group (n = 56)	MINS group (n = 24)	t value	P value
SBP (mmHg)	T0	155.93 ± 20.05	153.79 ± 13.73	0.476	0.636
	T6	143.61 ± 16.41	147.21 ± 21.15	-0.823	0.413
DBP (mmHg)	T0	79.61 ± 12.38	80.88 ± 11.99	-0.424	0.673
	T6	74.27 ± 10.48	76.79 ± 8.34	-1.045	0.299
HR (bpm)	T0	73.86 ± 11.17	72.17 ± 14.04	0.573	0.568
	T6	72.73 ± 11.95	71.79 ± 12.56	0.318	0.752
Glu (mmol/L)	T0	6.11 ± 1.54	6.47 ± 1.96	-0.891	0.376
	T4	7.16 ± 1.68	7.01 ± 1.32	0.401	0.689
Lac (mmol/L)	T0	0.99 ± 0.44	0.88 ± 0.44	1.022	0.310
	T4	0.74 ± 0.33	0.73 ± 0.33	0.117	0.907
PaCO₂ (mmHg)	T0	41.14 ± 5.69	41.33 ± 7.22	-0.121	0.904
	T4	47.20 ± 6.24	47.46 ± 6.88	-0.163	0.871

SBP: Systolic blood pressure; DBP: Diastolic blood pressure; HR: Heart rate; Glu: Glucose; Lac: Lactate; PaCO₂: Partial pressure of carbon dioxide; MINS: Myocardial injury after non-cardiac surgery.

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Citation: Ma TT, Tong J, Liu MY. Cardioprotective effects of remimazolam in elderly hypertensive patients undergoing gastrointestinal tumor surgery: A randomized controlled trial. World J Gastrointest Oncol 2026; 18(8): 121785
URL: https://www.wjgnet.com/1948-5204/full/v18/i8/121785.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i8.121785

Ma TT, Tong J, Liu MY. Cardioprotective effects of remimazolam in elderly hypertensive patients undergoing gastrointestinal tumor surgery: A randomized controlled trial. World J Gastrointest Oncol 2026; 18(8): 121785 [DOI: 10.4251/wjgo.v18.i8.121785]

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