Quantitative TP53 circulating tumor DNA predicts tumor response and survival outcomes in esophageal squamous cell carcinoma

doi:10.4251/wjgo.120942

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Aug 15, 2026; 18(8): 120942
Published online Aug 15, 2026. doi: 10.4251/wjgo.120942

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Figure 4 Receiver operating characteristic analysis of preoperative TP53 circulating tumor DNA for lymph node metastasis prediction. The analysis yields an area under the curve of 0.704, indicating the potential of TP53 circulating tumor DNA variant allele frequency as a predictive biomarker for nodal metastasis. AUC: Area under the curve; CI: Confidence interval.

Citation: Gu RT, Liu T, Piao ZS, Jin H, Wang XW, Li X. Quantitative TP53 circulating tumor DNA predicts tumor response and survival outcomes in esophageal squamous cell carcinoma. World J Gastrointest Oncol 2026; 18(8): 120942
URL: https://www.wjgnet.com/1948-5204/full/v18/i8/120942.htm
DOI: https://dx.doi.org/10.4251/wjgo.120942

Gu RT, Liu T, Piao ZS, Jin H, Wang XW, Li X. Quantitative TP53 circulating tumor DNA predicts tumor response and survival outcomes in esophageal squamous cell carcinoma. World J Gastrointest Oncol 2026; 18(8): 120942 [DOI: 10.4251/wjgo.120942]

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