Prophylactic cholecystectomy for asymptomatic gallstone disease: Two case reports and review of literature

doi:10.4251/wjgo.v18.i8.120889

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Aug 15, 2026; 18(8): 120889
Published online Aug 15, 2026. doi: 10.4251/wjgo.v18.i8.120889

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Figure 5 Biopsy pathology of the second case. The biopsy pathology of the second case revealed poorly differentiated carcinoma, and immunohistochemistry staining suggested positive cytokeratin 7, cytokeratin 19, caudal-type homeobox transcription factor 2 and human epidermal growth factor receptor 2. HE: Hematoxylin and eosin; CK: Cytokeratin; CDX2: Caudal-type homeobox transcription factor 2; Her-2 (4B5): Human epidermal growth factor receptor 2; AR: Androgen receptor; Arg-1: Arginase-1; CD: Cluster of differentiation; CPC: Chorionic papillary carcinoma; PAX: Paired box gene; PSA: Prostate-specific antigen; TFE: Transcription factor E.

Citation: Zhang J, Xi B, Li J, Wen L, Deng Y, Wang CW, Zhang Y. Prophylactic cholecystectomy for asymptomatic gallstone disease: Two case reports and review of literature. World J Gastrointest Oncol 2026; 18(8): 120889
URL: https://www.wjgnet.com/1948-5204/full/v18/i8/120889.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i8.120889

Zhang J, Xi B, Li J, Wen L, Deng Y, Wang CW, Zhang Y. Prophylactic cholecystectomy for asymptomatic gallstone disease: Two case reports and review of literature. World J Gastrointest Oncol 2026; 18(8): 120889 [DOI: 10.4251/wjgo.v18.i8.120889]

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