Prophylactic cholecystectomy for asymptomatic gallstone disease: Two case reports and review of literature

doi:10.4251/wjgo.v18.i8.120889

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Aug 15, 2026; 18(8): 120889
Published online Aug 15, 2026. doi: 10.4251/wjgo.v18.i8.120889

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Figure 3 Biopsy pathology of the first case showing no evidence of tumor. Hematoxylin and eosin staining showed necrosis of liver tissue, with chronic inflammatory cell infiltration and proliferation of fibrous tissue, in accordance with the positive cluster of differentiation 3 (CD3) and CD20 staining. Other immunohistochemistry assays suggested positive cytokeratin 7 and CD56 staining, and negative staining for hepatitis B surface antigen, cytomegalovirus type 2, and Epstein-Barr virus-encoded small RNAs. HE: Hematoxylin and eosin; HBS: Hepatitis B surface antigen; CMV2: Cytomegalovirus type 2; EBER: Epstein-Barr virus-encoded small RNAs; CK: Cytokeratin; CD: Cluster of differentiation.

Citation: Zhang J, Xi B, Li J, Wen L, Deng Y, Wang CW, Zhang Y. Prophylactic cholecystectomy for asymptomatic gallstone disease: Two case reports and review of literature. World J Gastrointest Oncol 2026; 18(8): 120889
URL: https://www.wjgnet.com/1948-5204/full/v18/i8/120889.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i8.120889

Zhang J, Xi B, Li J, Wen L, Deng Y, Wang CW, Zhang Y. Prophylactic cholecystectomy for asymptomatic gallstone disease: Two case reports and review of literature. World J Gastrointest Oncol 2026; 18(8): 120889 [DOI: 10.4251/wjgo.v18.i8.120889]

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