Impact of combined pregabalin and multimodal analgesia on cancer pain and quality of life in advanced colorectal cancer

Table 3 Comparison of quality of life (cancer patient quality of life core scale) scores between the two groups of patients before and after intervention

Dimensions	Group	Before intervention	After intervention	t	P value
Overall health	Observation group (n = 50)	42.3 ± 8.6	68.5 ± 10.2	7.85	< 0.001
	Control group (n = 50)	41.8 ± 8.9	52.4 ± 9.6
E-emotional function	Observation group (n = 50)	50.2 ± 9.3	72.3 ± 9.8	6.52	< 0.001
	Control group (n = 50)	49.7 ± 9.5	58.7 ± 10.1
Cognitive function	Observation group (n = 50)	48.5 ± 10.1	70.6 ± 10.5	6.98	< 0.001
	Control group (n = 50)	48.1 ± 9.8	56.3 ± 9.9
Tired	Observation group (n = 50)	58.6 ± 9.2	32.1 ± 8.4	7.23	< 0.001
	Control group (n = 50)	59.1 ± 9.4	45.6 ± 9.2
Pain	Observation group (n = 50)	65.3 ± 8.7	28.3 ± 7.6	8.65	< 0.001
	Control group (n = 50)	64.9 ± 8.9	42.8 ± 8.7
Insomnia	Observation group (n = 50)	57.8 ± 9.0	30.5 ± 8.2	7.51	< 0.001
	Control group (n = 50)	58.2 ± 9.3	44.3 ± 9.1

P < 0.05 for comparisons before and after intervention within the group; the higher the score of functional and overall health status dimensions and the lower the score of symptom dimension, the better the quality of life.