Impact of sintilimab plus anlotinib on progression-free survival in advanced unresectable hepatocellular carcinoma

doi:10.4251/wjgo.v18.i8.119966

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Aug 15, 2026; 18(8): 119966
Published online Aug 15, 2026. doi: 10.4251/wjgo.v18.i8.119966

Table 5 Comparison of adverse reaction incidence between the two groups of patients, n (%)

Type of adverse reaction	Experimental group (n = 45)	Control group (n = 45)	χ²	P value
Hypertension	12 (26.7)	9 (20.0)	0.632	0.427
Proteinuria	8 (17.8)	6 (13.3)	0.456	0.499
Diarrhea	10 (22.2)	8 (17.8)	0.358	0.549
Rash	9 (20.0)	7 (15.6)	0.369	0.544
Hypothyroidism	7 (15.6)	6 (13.3)	0.121	0.728
Grade 1-2 adverse reactions	38 (84.4)	36 (80.0)	0.342	0.559
Grade 3-4 adverse reactions	4 (8.9)	3 (6.7)	0.162	0.687
Total adverse reactions	40 (88.9)	37 (82.2)	0.815	0.367

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Citation: Sheng C, Li H. Impact of sintilimab plus anlotinib on progression-free survival in advanced unresectable hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(8): 119966
URL: https://www.wjgnet.com/1948-5204/full/v18/i8/119966.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i8.119966

Sheng C, Li H. Impact of sintilimab plus anlotinib on progression-free survival in advanced unresectable hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(8): 119966 [DOI: 10.4251/wjgo.v18.i8.119966]

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